Continued Operation and Maintenance Support for Agilent Seahorse

The Agilent Seahorse Analyzer housed in Building 35A, Pod D, is a shared core resource utilized by multiple laboratories and Institutes/Centers (ICs) within the NIH intramural research program. This highly specialized metabolic analyzer is critical for real-time measurement of cellular bioenergetics, specifically oxygen consumption rate (OCR) and extracellular acidification rate (ECAR), which are essential for evaluating mitochondrial respiration and glycolysis. The instrument plays a key role in advancing research related to cancer metabolism, neurodegeneration, immunology, and mitochondrial diseases. Consistent operational performance of this system is essential to ensure data quality, experimental reproducibility, and timely progress of high-priority research efforts.