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Notice ID: a01af4b233824257bcb2807f114c4cd6Solicitation

Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINE)

Responses closed . Solicitation posted by DEPT OF DEFENSE (DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)) on September 28, 2026. Solicitation DARPA-PA-25-07-06.

NAICS 541715 (Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)). Original response deadline: . Full description on SAM.gov.

Description

The Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) is issuing a Disruption Opportunity (DO), inviting submissions of innovative basic or applied research concepts in the technical domain of targeted neuroplasticity. This DO is issued under the Program Announcement for Disruptioneering, DARPA-PA-25-07 Amendment 1. All awards will be made in the form of an Other Transaction (OT) for Prototype Agreement. The total award value for this DO is limited to $2,000,000 per award. This total award value includes Government funding and performer cost share if required or proposed.

Full description on SAM.gov

Overview

Agency:
Department of WarDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
Office:DEF ADVANCED RESEARCH PROJECTS AGCY
Posted:September 28, 2026
NAICS:541715: Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Last Updated:Sep 28, 2026
PSC:AC11: NATIONAL DEFENSE R&D SERVICES; DEPARTMENT OF DEFENSE - MILITARY; BASIC RESEARCH
Response Deadline:
Set-Aside:Not specified
Type:Solicitation
Place of Performance:Not specified

Award Overview

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Primary Contact

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Documents

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SolicitationDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)Sep 28, 202628.72 KB
SolicitationDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)Sep 28, 2026193.63 KB
SolicitationDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)Sep 28, 202636.1 KB
SolicitationDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)Sep 28, 202625.83 KB
SolicitationDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)Sep 28, 2026195.55 KB

Lifecycle

Solicitation:DARPA-PA-25-07-06
  1. Solicitation

Award typically follows within 30–90 days after the response deadline. (estimate)

  1. 3×
    SolicitationCurrentAug 28, 2026

    Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINE)

    Notice a01af4b233824257bcb2807f114c4cd6 on SAM.gov

Similar Opportunities

Title
Phase
Agency
NAICS
Set Aside
Posted
Deadline
Location
The mission of the DARPA DSO is to identify, investigate, and leverage nascent scientific advances for national security applications by pursuing high-risk, high-payoff research initiatives across a broad spectrum of science and engineering disciplines. Disruption Opportunity (DO) topics are issued to rapidly investigate new concepts with focused investments. DOs enable DARPA to initiate a new investment for unclassified efforts in less than 120 calendar days from idea inception. To enable this approach, DSO will issue individual DOs under this solicitation. These opportunities will target specific technical domains important to DSO’s mission to pursue innovative research that leads to a prototype demonstration. More information about DSO’s technical domains and research topics of interest may be found at https://www.darpa.mil/about/offices/dso.
Solicitation541715No Set-Aside09/25/202610/30/2026-
The mission of the DARPA DSO is to identify, investigate, and leverage nascent scientific advances for national security applications by pursuing high-risk, high-payoff research initiatives across a broad spectrum of science and engineering disciplines. Disruption Opportunity (DO) topics are issued to rapidly investigate new concepts with focused investments. DOs enable DARPA to initiate a new investment for unclassified efforts in less than 120 calendar days from idea inception. To enable this approach, DSO will issue individual DOs under this solicitation. These opportunities will target specific technical domains important to DSO’s mission to pursue innovative research that leads to a prototype demonstration. More information about DSO’s technical domains and research topics of interest may be found at https://www.darpa.mil/about/offices/dso.
Solicitation541715No Set-Aside09/11/202610/30/2026-
This Research Solutions Opening (RSO) aims to strengthen the DARPA Program Manager (PM) community by engaging academic researchers capable of addressing DARPA's hard problems. PMs that are passionate about tackling the most complex technical challenges, pushing the boundaries of science and technology, and shaping the future of defense and innovation. Together, through this effort, we will pioneer revolutionary solutions, foster interdisciplinary collaboration, and empower the brightest minds to make the impossible possible. This RSO also seeks to fund the independent research ideas of these passionate researchers. This RSO is limited to Intergovernmental Personnel Act (IPA) candidates and proposals from accredited U.S. colleges and universities.
Solicitation541715No Set-Aside09/03/202606/01/2027-
The Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) is issuing a Disruption Opportunity (DO), inviting submissions of innovative basic or applied research concepts in the technical domain of targeted neuroplasticity. This DO is issued under the Program Announcement for Disruptioneering, DARPA-PA-25-07 Amendment 1. All awards will be made in the form of an Other Transaction (OT) for Prototype Agreement. The total award value for this DO is limited to $2,000,000 per award. This total award value includes Government funding and performer cost share if required or proposed.
Solicitation541715No Set-Aside09/03/202610/09/2026-
The Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) is issuing a Disruption Opportunity (DO), inviting submissions of innovative basic or applied research concepts in the technical domain of targeted neuroplasticity. This DO is issued under the Program Announcement for Disruptioneering, DARPA-PA-25-07 Amendment 1. All awards will be made in the form of an Other Transaction (OT) for Prototype Agreement. The total award value for this DO is limited to $2,000,000 per award. This total award value includes Government funding and performer cost share if required or proposed.
Solicitation541715No Set-Aside08/28/202610/09/2026-

Additional Details

Solicitation Number

DARPA-PA-25-07-06

Archive Date

Nov 8, 2026

Office Address

ARLINGTON, VA, 222032114