Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
Active, responses due . Full description on SAM.gov.
Overview
- Response deadline
- 11:59 PM EST
- Posted
- January 8, 2026
- Notice type
- Solicitation
- NAICS
- 541715: Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Agency
- Department of Health and Human ServicesNATIONAL INSTITUTES OF HEALTH
Notice details
- Office
- ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
- PSC
- AN13: HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
- Last updated
- Oct 28, 2026
- First published
- Last updated on SAM.gov
Identifiers
- Solicitation number
- ARPA-H-SOL-24-103
- Notice ID
- 2d1209273c284cb48ea9898939f7c3f8
Description
This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSO’s interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care.
- Solution summary submissions must be submitted to: https://solutions.arpa-h.gov
- Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/
- Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/
Amendment 3 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the prior solicitation(s) will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The following updates were made to the proposal documents:
1) Administrative & National Policy Requirements Document
- Updated the instructions and references within the “Organizational Conflicts of Interest (OCI) Affirmations and Disclosure” section.
- Updated questions, instructions, and content within the “Research Security Disclosure” section.
- Updated the instructions and intellectual property data assertions charts within the “IP” section. This included providing definitions of rights categories (unlimited, government purpose, limited, and specially negotiated/other) and consolidating two data assertions charts into one to assist proposers more efficiently complete the document. Specifically, the “Non-Commercial” and “Commercial” tables were removed and replaced with the “Background IP and Data Assertions” table.
- Eliminated the “Software Component Standards” section.
- Updated the Human Subjects Research (HSR) table within the “HSR” section.
- Updated the Animal Subjects Research (ASR) table within the “ASR” section.
- Updated the questions and instructions within the “Biosecurity” section.
2) Cost Proposal Document (Word document)
- Updated the instructions within the “Level of Effort and Labor Costs” section. Added definitions for “burdened labor rate” and “fully burdened labor rate” to provide clarity for proposers when completing the document. Also added a statement to clarify that fully burdened labor rates are not used in the Cost Proposal Workbooks.
- Increased the threshold for proposers to provide supporting documentation with their proposal for planned materials and equipment purchases based on unit cost. The unit cost threshold was increased from $5,000 to $10,000.
3) Cost Proposal Workbooks (Excel spreadsheets)
- Updated instructions to clarify that ARPA-H will assume profit/fee is not applicable for proposals if proposers do not include profit/fee in the workbook.
- Updated the instructions for supporting documentation associated with planned materials and equipment purchases (based on the unit cost threshold increasing from $5,000 to $10,000).
- Completed administrative update to a tab
Award Overview
Contacts
Contracting Officer
Primary Contact
Documents
Lifecycle
- 1Version 1Solicitation
Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
- 2Version 2Solicitation
Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
- 3Version 3Solicitation
Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
- 4Version 4Solicitation
Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
- 5Version 5Solicitation
Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
- 6Version 6Solicitation
Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
- 7Version 7Solicitation
Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
- 8Version 8Solicitation
Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
- 9Version 9SolicitationCurrent
Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
Similar Opportunities
Additional Details
Solicitation Number
ARPA-H-SOL-24-103
Archive Date
Mar 20, 2029
Office Address
Washington, DC, 20005