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Notice ID: 2d1209273c284cb48ea9898939f7c3f8Solicitation

Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)

Active, responses due . Full description on SAM.gov.

Overview

Response deadline
11:59 PM EST
Posted
January 8, 2026
Notice type
Solicitation
NAICS
541715: Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Agency
Department of Health and Human ServicesNATIONAL INSTITUTES OF HEALTH

Notice details

Office
ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
PSC
AN13: HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
Last updated
Oct 28, 2026
First published
Last updated on SAM.gov

Identifiers

Solicitation number
ARPA-H-SOL-24-103
Notice ID
2d1209273c284cb48ea9898939f7c3f8

Description

This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSO’s interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care.

  • Solution summary submissions must be submitted to: https://solutions.arpa-h.gov
  • Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/
  • Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/

Amendment 3 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the prior solicitation(s) will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The following updates were made to the proposal documents:   

1) Administrative & National Policy Requirements Document

  • Updated the instructions and references within the “Organizational Conflicts of Interest (OCI) Affirmations and Disclosure” section.
  • Updated questions, instructions, and content within the “Research Security Disclosure” section.
  • Updated the instructions and intellectual property data assertions charts within the “IP” section. This included providing definitions of rights categories (unlimited, government purpose, limited, and specially negotiated/other) and consolidating two data assertions charts into one to assist proposers more efficiently complete the document. Specifically, the “Non-Commercial” and “Commercial” tables were removed and replaced with the “Background IP and Data Assertions” table.
  • Eliminated the “Software Component Standards” section.
  • Updated the Human Subjects Research (HSR) table within the “HSR” section.
  • Updated the Animal Subjects Research (ASR) table within the “ASR” section.
  • Updated the questions and instructions within the “Biosecurity” section.

2) Cost Proposal Document (Word document)

  • Updated the instructions within the “Level of Effort and Labor Costs” section. Added definitions for “burdened labor rate” and “fully burdened labor rate” to provide clarity for proposers when completing the document. Also added a statement to clarify that fully burdened labor rates are not used in the Cost Proposal Workbooks.
  • Increased the threshold for proposers to provide supporting documentation with their proposal for planned materials and equipment purchases based on unit cost. The unit cost threshold was increased from $5,000 to $10,000.

3) Cost Proposal Workbooks (Excel spreadsheets)

  • Updated instructions to clarify that ARPA-H will assume profit/fee is not applicable for proposals if proposers do not include profit/fee in the workbook.
  • Updated the instructions for supporting documentation associated with planned materials and equipment purchases (based on the unit cost threshold increasing from $5,000 to $10,000).
  • Completed administrative update to a tab

Full description on SAM.gov

Award Overview

Contacts

Contracting Officer

Primary Contact

Documents

Files (3)

  • Appendix A - ARPA-H Solutions Summary Template-Amend-3.docx

    39 KBAdded in Solicitation version 7Posted
    Download
  • Bundle_of_Attachments_Amend_3.zip

    1.1 MBAdded in Solicitation version 9Posted
    Download
  • RSO_MO_ISO_AMEND_3.pdf

    163 KBAdded in Solicitation version 6Posted
    Download

Lifecycle

  1. 1
    Version 1Solicitation

    Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)

    Notice 76679cd8810f40229694c60c0a593302 on SAM.gov

  2. 2
    Version 2Solicitation

    Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)

    Notice 12060296542746d5a0845f26c43487bc on SAM.gov

  3. 3
    Version 3Solicitation

    Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)

    Notice 3b131b790c8f4607b3c7214b93156018 on SAM.gov

  4. 4
    Version 4Solicitation

    Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)

    Notice ecbf2716b6e648e69dd2eec1a79ab027 on SAM.gov

  5. 5
    Version 5Solicitation

    Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)

    Notice c575f73500844322be760e0d98c233ac on SAM.gov

  6. 6
    Version 6Solicitation

    Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)

    Notice 2fe82425541c4b6f92713d9812721be4 on SAM.gov

  7. 7
    Version 7Solicitation

    Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)

    Notice 36eb58892e1f49f897c81d87ff7a95fe on SAM.gov

  8. 8
    Version 8Solicitation

    Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)

    Notice afb42f0cb40041baa180f7413ba2f7b1 on SAM.gov

  9. 9
    Version 9SolicitationCurrent

    Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)

    Notice 2d1209273c284cb48ea9898939f7c3f8 on SAM.gov

Similar Opportunities

Additional Details

Solicitation Number

ARPA-H-SOL-24-103

Archive Date

Mar 20, 2029

Office Address

Washington, DC, 20005