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Notice ID: 7cc49984be44476e8798ab0e0c1f253bSolicitation

High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

Responses closed . Full description on SAM.gov.

Overview

Response deadline
3:00 PM EST
Posted
October 28, 2026
Notice type
Solicitation
NAICS
541714: Research and Development in Biotechnology (except Nanobiotechnology)
Agency
Department of WarDEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)

Notice details

Office
DEF ADVANCED RESEARCH PROJECTS AGCY
PSC
AC12: NATIONAL DEFENSE R&D SERVICES; DEPARTMENT OF DEFENSE - MILITARY; APPLIED RESEARCH
Last updated
Oct 28, 2026
First published
Last updated on SAM.gov

Identifiers

Solicitation number
DARPA-PA-27-01
Notice ID
7cc49984be44476e8798ab0e0c1f253b

Description

UPDATE: The purpose of Amendment 1 to DARPA-PA-27-01, the HUBBLE Program Announcement (PA), is to update Attachment B and the verbiage in Section 4.1.2 and Section 7.8 of the Program Announcement.

The Defense Advanced Research Projects Agency (DARPA) is soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions. Utility of this capability will be demonstrated in identifying novel diagnostic and therapeutic targets within the interaction space underlying including traumatic brain injury.

Full description on SAM.gov

Award Overview

Contacts

Contracting Officer

Primary Contact

Dr. Abhishek Singharoy, DARPA/BTO

Documents

Files (8)

  • DARPA-PA-27-01-Amendment-01.pdf

    748 KBAdded in Solicitation version 2Posted
    Download
  • Attachment_B_DARPA-PA-27-01__Model_OT_for_Research_HUBBLE_20261022.docx

    117 KBAdded in Solicitation version 2Posted
    Download
  • DARPA-PA-27-01.pdf

    960 KBAdded in Solicitation version 1Posted
    Download
  • Attachment_F_Risk_Matrix_HUBBLE.pptx

    89 KBAdded in Solicitation version 1Posted
    Download
  • Attachment_E_Task_Description_Document_HUBBLE.docx

    30 KBAdded in Solicitation version 1Posted
    Download
  • Attachment_D_Schedule_Milestone_and_Payments.xlsx

    28 KBAdded in Solicitation version 1Posted
    Download
  • Attachment_C_Cost_Proposal_Spreadsheet_HUBBLE.xlsx

    553 KBAdded in Solicitation version 1Posted
    Download
  • Attachment_A_Abstract_Template_and_Instructions__Phase_1_.docx

    45 KBAdded in Solicitation version 1Posted
    Download

Lifecycle

  1. 1
    Version 1Solicitation

    High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

    Notice 98c034706e4b430281ead1c3497e9d72 on SAM.gov

  2. 2
    Version 2SolicitationCurrent

    High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

    Notice 7cc49984be44476e8798ab0e0c1f253b on SAM.gov

Similar Opportunities

Additional Details

Solicitation Number

DARPA-PA-27-01

Archive Date

Jan 10, 2027

Office Address

ARLINGTON, VA, 222032114